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In contrast, human clinical evidenceincluding decades of research on NAD+ precursors like niacin, nicotinamide, NR, and NMNhas found no association with increased cancer risk

The study was supported by grants from the Investigation Committee on Ossification of Spinal Ligaments, Public Health Bureau of the Japanese Ministry of Labor, Health and Welfare, and four grants-in-aid for Scientific Research (#25K12523, #25K12454, #25K20005, #23K08628)